Proliferating cell nuclear antigen (PCNA) is a well-documented accessory protein of DNA repair and replication.It belongs to the sliding clamp family of proteins that encircle DNA and acts as a mobile docking platform for interacting proteins to mount and perform their metabolic tasks.PCNA presence is ubiquitous to all cells, and when located in th
On the Unambiguous Distance of Multicarrier Phase Ranging With Random Hopped Frequencies
Multicarrier phase ranging (MCPR) technique has been widely used in radio navigation, telemetry, radar, and many other fields.In an MCPR system, unique range estimation can be obtained within only the so-called unambiguous distance (UD) because of phase ambiguity.As a metric gauging, the measurable distance of an MCPR system, the UD has been well s
Trigger finger presenting secondary to leiomyoma: a case report
Abstract Introduction We Briefs and Diapers present a previously undescribed entity: trigger finger secondary to a leiomyoma.This is the first time such a case has been reported and highlights the fact that common conditions can sometimes present secondary to rare diseases.Case presentation A 39-year-old Caucasian man presented with a fairly typica
Linking Oxidative Stress and DNA Damage to Changes in the Expression of Extracellular Matrix Components
Cells are subjected to endogenous [e.g., reactive oxygen species (ROS), replication stress] and exogenous insults (e.g., UV light, ionizing radiation, and certain chemicals), which can affect the synthesis and/or stability of different macromolecules required for cell and tissue function.Oxidative stress, caused by excess ROS, and DNA damage, trigg
Histological and Immunohistochemical Characterization of a Case of Endometriosis in a Guinea Pig (Cavia tschudii)
Endometriosis is a chronic gynecological Serrapeptase disease characterized by the ectopic proliferation of endometrial tissue outside of the uterine cavity.The pathogenesis of this disease is still obscure, and Sampson’s theory of retrograde menstruation is still the most widely accepted explanation.Endometriosis in animals has been so far descr